ÁÖÀÓ±³¼ö (M.D., Ph.D. ¿¬¼¼´ëÇб³)
  ¼ÒÈ­±â¾à¸®, »óÇǼ¼Æ÷ÇÐ
  ¾à¹°¼ö¼ÛüÀ¯ÀüüÁßÁ¡¿¬±¸¼¾ÅÍ
  2228-1737
  mlee@yuhs.ac
 
 

1. Kim, K.H., Lee, M.G., Kim, D.G. (1996) A cholecystokinin receptor antagonist L364,718
ameliorates the signs of experimental pancreatitis in rats. Int. J. Pancreatol. 20, 205-211

2. Lee, M.G., Kim, K.H., Park, K.Y., Kim, J.S. (1996) Evaluation of anti-influenza effects of
camostat in mice infected with non-adapted human influenza viruses. Arch. Virol.
141, 1979-1989

3. Park K.Y., Lee, M.G., Ryu, J.C. (1997)Evolutionary stasis of M1 gene of human influenza A
viruses and the possibility of their subtyping by restriction analysis of M1 gene polymerase
chain reaction product. Acta Virologica 41, 231-239

4. Zeng, W., Lee, M.G., Yan, M., Diaz, J., Benjamin, I., Marino, C.R., Kopito, R., Freedman,
S., Cotton, C., Muallem, S., Thomas, P. (1997) Immuno and functional characterization
of CFTR in submandibular and pancreatic acinar and duct cells. Am. J. Physiol. 273, C442-C455

5. Lee, M.G., Xu, X., Zeng, W., Diaz, J., Kuo, T.H., Wuytack, F., Racymaekers, L., Muallem, S.
(1997) Polarized expression of Ca2 pumps in pancreatic and salivary gland cells. Role in
initiation and propagation of [Ca2]i waves. J. Biol. Chem. 272, 15771-15776

6. Lee, M.G., Xu, X., Zeng, W., Diaz, J., Wojcikiewicz, R.J., Kuo, T.H., Wuytack, F., Racymaekers,
L., Muallem, S. (1997) Polarized expression of Ca2 channels in pancreatic and salivary
gland cells. Correlation with initiation and propagation of [Ca2]i waves. J. Biol. Chem.
272, 15765-15770

7. Muallem, S., Lee, M.G. (1997) High [Ca2]i domains, secretory granules and exocytosis.
Cell Calcium 22, 1-4

8. Zeng, W., Lee, M.G., Muallem, S. (1997) Membrane-specific regulation of Cl- channels by
purinergic receptors in rat submandibular gland acinar and duct cells. J. Biol. Chem. 272,
32956-32965

9. Lee, M.G., Zeng, W., Muallem, S. (1997) Characterization and localization of P2 receptors in rat
submandibular gland acinar and duct cells. J. Biol. Chem. 272, 32951-32955

10. Lee, M.G., Schultheis, P.J., Yan, M., Shull, G., Bookstein, C., Chang, E, Donowitz, M.,
Park, K., Muallem, S. (1998) Membrane limited expression and regulation of Na+H
exchanger isoforms by P2 receptors in the rat submandibular duct. J. Physiol. (London) 513, 341-357

11. Lee, M.G., Wigley, W.C., Zeng, W., Noel, L.E., Marino, C.R., Thomas, P.J., Muallem, S.
(1999) Regulation of Cl-/HCO3- exchange by cystic fibrosis transmembrane conductance
regulator expressed in NIH 3T3 and HEK 293 cells. J. Biol. Chem. 274, 3414-3421

12. Wigley, C.W., Fabunmi, R.P., Lee, M.G., Marino, C.R., Muallem, S., DeMartino, G.N., Thomas, P.J.
(1999) Dynamic association of proteasomal machinery with the centrosome. J. Cell Biol.
145, 481-490

13. Luo, X., Zheng, W., Yan, M., Lee, M.G., Muallem, S. (1999) Multiple functional P2X and P2Y
receptors in the luminal and basolateral membranes of pancreatic duct cells. Am. J. Physiol.
277, C205-C215

14. Lee, M.G., Choi, J.Y., Luo, X., Strickland, E., Thomas, P.J., Muallem, S.
(1999) Cystic fibrosis transmembrane conductance regulator regulates luminal Cl-/HCO3-
exchange in mouse submandibular and pancreatic ducts. J. Biol. Chem. 274, 14670-14677

15. Moon, S.J., Ahn, W., Lee, M.G., Kim H., Lee, S.I., Seo, J.T., Case, R.M., Kim, K.H.
(2000) A novel effect of rebamipide: generation of [Ca2]i oscillations through activation
of CCK, receptors in rat pancreatic acinar cells. Eur. J. Pharmacol, 388, 17-20

16. Choi, J.Y., Shah, M., Lee, M.G., Schultheis, P.J., Shull, G., Muallem, S., Baum, M.
(2000) Novel amiloride-sensitive sodium-dependent proton secretion in the mouse proximal
convoluted tubule. J. Clin. Invest. 105, 1141-1146

17. Lee, M.G., Ahn, W., Choi, J.Y., Luo, X., Seo, J.T., Schultheis, P.J., Shull, G.E., Kim, K.H., Muallem, S.
(2000) Na+dependent transporters mediate HCO3- salvage across the luminal membrane of
the main pancreatic duct. J. Clin. Invest. 105, 1651-1658

18. Chung, K.C., Sung, J.Y., Ahn, W., Rhim, H., Oh, T.H., Lee, M.G., Ahn, Y.S.
(2001) Intracellular Calcium mobilization Induces Immediate Early Gene pip92 via Src and
MAP Kinase in Immortalized Hippocampal Cells. J Biol Chem. 276, 2132-2138

19. Choi, J.Y., Muallem, D., Kiselyov, K., Lee, M.G., Thomas, P.J., Muallem, S.
(2001) Aberrant CFTR-dependent HCO3- transport in mutations associated with cystic fibrosis.
Nature 410, 94-97

20. Luo, X., Choi, J.Y., Ko, S.B., Pushkin, A., Kurtz, I., Ahn, W., Lee, M.G., Muallem S.
(2001) HCO3- salvage mechanisms in the submandibular gland acinar and duct cells.
J Biol Chem. 276, 9808-9816

21. Ahn, W., Kim, K.H., Lee, J.A., Kim, J.Y., Choi, J.Y., Moe, O.W., Milgram, S.L., Muallem, S., Lee, M.G.
(2001) Regulatory Interaction between CFTR and HCO3- Salvage Mechanisms in Model Systems
and the Mouse Pancreatic Duct. J. Biol. Chem. 276, 17236-17243

22. Lee, M.G., Ahn, W., Lee, J.A., Kim, J.Y., Choi, J.Y., Moe, O.W., Milgram, S.L., Muallem, S., Kim, K.H.(2001) Coordination of pancreatic HCO3- secretion by protein-protein interaction between membrane transporters. JOP. 2001 Jul;2(4 Suppl):203-6. Review.

23. Jung, Y., Ha, H., Jung, S.H., Lee, M.G., Lee, H.W., Yoon, J., Choi, J.W., Yeh, B.I.(2001) F508 amino acid deletion mutation of CFTR gene in Korean lung cancer patients. Exp Mol Med. 33(1):29-31.

24. Wigley, W.C., Corboy, M.J., Cutler, T.D., Thibodeau, P.H., Oldan, J., Lee, M.G., Rizo, J.,
Hunt, J.F., Thomas, P.J. (2002) Protein sequence can encode native structure by disfavoring
alternate conformations. Nat. Struct. Biol. 9, 381-388

25. Kim, J.Y., Kim, K.H., Lee, J.A, Namkung, W., Sun, A-Q., Ananthanarayanan, M., Suchy, F.J.,
Shin, D.M., Muallem, S., Lee, M.G. (2002) Transporter-mediated bile acid uptake causes
Ca2+dependent cell death in rat pancreatic acinar cells. Gastroenterology 122, 1941-1953

26. Ko, S.B., Shcheynikov, N., Choi, J.Y., Luo, X., Ishibashi, K., Thomas, P.J., Kim, J.Y., Kim, K.H.,
Lee, M.G., Naruse, S., Muallem, S. (2002) A molecular mechanism for aberrant CFTR-
dependent HCO3- transport in cystic fibrosis. EMBO J. 21, 5662-5672

27. Park, M., Ko, S.B., Choi, J.Y., Muallem, G., Thomas, P.J., Pushkin, A., Lee, M.-S., Kim, J Y.,
Lee, M.G., Muallem, S., Kurtz, I. (2002) The cystic fibrosis transmembrane conductance
regulator (CFTR) interacts with and regulates the activity of the HCO3- salvage transporter
hNBC3. J. Biol. Chem. 277, 50503-50509

28. Namkung, W., Lee, J.A., Ahn, W., Han, W.S., Kwon, S.W., Ahn, D.S., Kim, K.H., Lee, M.G.
(2003) Ca2 activates CFTR- and Cl--dependent HCO3- transport in pancreatic duct cells.
J. Biol. Chem. 278, 200-207

29. Ahn, W., Lee, M.G., Kim, K.H., Muallem, S. (2003) Multiple Effects of SERCA2b Mutations
Associated with Darier's Disease. J. Biol. Chem. 278, 20795-20801.

30. Lee, J.H., Choi, J.H., Namkung, W., Hanrahan, J.W., Chang, J., Song, S.Y., Park, S.W.,
Kim, D.S., Yoon, J.-H., Suh, Y., Jang, I.-J., Nam, J.H., Kim, S.J., Cho, M.-O., Lee, J.-E.,
Kim, K.H., Lee, M.G. (2003) A haplotype-based molecular analysis of CFTR mutations
associated with respiratory and pancreatic diseases. Hum. Mol. Genet.12, 2321-2332.

31. Kim, J.Y., Han, W., Namkung, W., Lee, J.H., Kim, K.H., Shin, H., Kim, E., Lee, M.G.
(2004) Inhibitory regulation of cystic fibrosis transmembrane conductance regulator
anion-transporting activities by Shank2. J Biol Chem. 279, 10389-10396

32. Shin, J.H., Namkung, W., Choi, J.Y., Yoon, J.H., Lee, M.G. (2004) Purinergic stimulation
induces Ca2+dependent activation of Na+K+2Cl-cotransporter in human nasal epithelia.
J Biol Chem. 279, 18567-18574

33. Namkung, W., Han, W., Luo, X., Muallem, S., Cho, K.H., Kim, K.H. Lee, M.G. (2004)
Protease-activated receptor 2 exerts local protection and mediates some systemic
complications in acute pancreatitis. Gastroenterology. 126, 1844-1859

34. Kim, C.H., Kim, S.S., Choi, J.Y., Shin, J.H., Kim, J.Y., Namkung, W., Lee, J.G., Lee, M.G., Yoon, J.H. (2004) Membrane-specific expression of functional purinergic receptors in normal human nasal epithelial cells. Am J Physiol Lung Cell Mol Physiol. 287:L835-L842

35. Lee, J.E., Choi, J.H., Lee, J.H., Lee, M.G. (2005) Gene SNPs and mutations in clinical genetic testing: haplotype-based testing and analysis. Mutat Res. 573:195-204

36. Namkung, W., Kim, K.H., Lee, M.G. (2005) Base treatment corrects defects due to misfolding of mutant CFTR. Gastroenterology 129:1979-1990

37. Shin, J.H., Namkung, W., Kim, C.H., Choi, J.Y., Yoo, J.B., Lee, K.D., Lee, J.G., Lee, M.G., Yoon, J.H.(2005) Expression of Na+/H+ exchanger isoforms in normal human nasal epithelial cells and functional activity of Na+/H+ exchanger 1 in intracellular pH regulation. Acta Otolaryngol. 125(3):286-92.

38. Han, W., Kim, K.H., Jo, M.J., Lee, J.H., Yang, J., Doctor, R.B., Moe, O.W., Lee, J., Kim, E., Lee, M.G. (2006) Shank2 associates with and regulates Na+/H+ exchanger 3. J Biol Chem. 281:1461-1469

39. Worley, P.F., Zeng, W., Huang, G.N., Yuan, J.P., Kim, J.Y., Lee, M.G., Muallem S. (2007) TRPC channels as STIM1-regulated store-operated channels. Cell Calcium 42:205-211.

40. Kim, J., Jung, Y.S., Han, W., Kim, M.Y., Namkung, W., Lee, B.H., Yi, K.Y., Yoo, S.E., Lee, M.G., Kim, K.H. (2007) Pharmacodynamic characteristics and cardioprotective effects of new NHE1 inhibitors. Eur J Pharmacol. 12;567:131-138.

41. Kim, S.J., Choi, J.Y., Son, E.J., Namkung, W., Lee, M.G., Yoon, J.H. (2007) Interleukin-1beta upregulates Na+-K+-2Cl- cotransporter in human middle ear epithelia. J Cell Biochem. 101:576-586.

42. Lee, J.H., Richter, W., Namkung, W., Kim, K.H., Kim, E., Conti, M., Lee, M.G. (2007) Dynamic regulation of cystic fibrosis transmembrane conductance regulator by competitive interactions of molecular adaptors. J Biol Chem. 282:10414-10422

43. Choi, J.H., Ahn, B.M., Yi, J., Lee, J.H., Lee, J.H., Chon, J.Y., Han, K-H., Ahn, S.H., Jang, I.J., Cho, J-Y., Suh, Y., Cho, M-O., Lee, J-E., Kim, K.H., Lee, M.G. (2007) MRP2 haplotypes confer differential susceptibility to toxic liver injury. Pharmacogenet Genomics, 17:403-415

44. Ishiguro, H., Namkung, W., Yamamoto, A., Wang, Z., Worrell, R.T., Xu, J., Lee, M.G., Soleimani, M. (2007) Effect of Slc26a6 deletion on apical Cl-/HCO3- exchanger activity and cAMP-stimulated bicarbonate secretion in pancreatic duct. Am J Physiol Gastrointest Liver Physiol. 292:G447-G455.

45. Shin, J.H., Son, E.J., Lee, H.S., Kim, S.J., Kim, K., Choi, J.Y., Lee, M.G., Yoon, J.H.(2007) Molecular and functional expression of anion exchangers in cultured normal human nasal epithelial cells. Acta Physiol (Oxf), 191(2):99-110

46. Namkung, W., Yoon, J.S., Kim, K.H., Lee, M.G. (2008) PAR2 Exerts Local Protection against Acute Pancreatitis via Modulation of MAP Kinase and MAP Kinase Phosphatase Signaling. Am J Physiol Gastrointest Liver Physiol. 295:G886-G894.

47. Lee, M.G., Muallem, S. (2008) Pancreatitis: the neglected duct. Gut 57: 1037-1039.

48. Yoon, J.S., Park, H.J., Yoo, S.Y., Namkung, W., Jo, M.J., Koo, S.K., Park, H.Y., Lee, W.S., Kim, K.H., Lee, M.G. (2008) Heterogeneity in the processing defect of SLC26A4 mutants. J Med Genet. 45:411-419.

49. Jung, Y.S., Kim, H.Y., Kim, J., Lee, M.G., Pouyssegur, J., Kim, E. (2008) Physical interactions and functional coupling between Daxx and sodium hydrogen exchanger 1 in ischemic cell death. J Biol Chem. 283:1018-1025.

50. Choi, J.H., Lee, M.G., Cho, J.Y., Lee, J.E., Kim, K.H., Park, K. (2008) Influence of OATP1B1 genotype on the pharmacokinetics of rosuvastatin in Koreans. Clin Pharmacol Ther. 83:251-257.

51. Gee, H.Y., Kim, Y.W., Jo, M.J., Namkung, W., Kim, J.Y., Park, H.W., Kim, K.S., Kim, H., Baba, A., Yang, J., Kim, E., Kim, K.H, Lee, M.G. (2009) Synaptic scaffolding molecule binds to and regulates vasoactive intestinal polypeptide type-1 receptor in epithelial cells. Gastroenterology 137:607-617.

52. Kim, J., Namkung, W., Yoon, J.S., Jo, M.J., Lee, S.H., Kim, K.H., Kim, J.Y., Lee, M.G. (2009) The role of translation elongation factor eEF1A in intracellular alkalinization-induced tumor cell growth. Lab Invest. 89:867-874.

53. Sohn, M.H., Lee, J.H., Kim, K.W., Kim, S.W., Lee, S.H., Kim, K.E., Kim, K.H., Lee, C.G., Elias, J.A., Lee, M.G. (2009) Genetic Variation in the Promoter Region of Chitinase 3-Like 1 (CHI3L1) is Associated with Atopy. Am J Respir Crit Care Med. 179:449-456

54. Yang, K.Y., Jung, K.Y., Cho, S.W., Choi, H.K., Kim, S.W., Kim, S.Y., Kim, H.J., Jang, C.H., Lee, M.G., Han, J. and Shin, C.S. Chloride intracellular channel 1 regulates osteoblast differentiation Bone 2009. Dec 45(6):1175-1185

55. Lee, B.K., Lee, D.H., Park, S., Park, S.L., Yoon, J.S., Lee, M.G., Lee, S., Yi, K.Y., Yoo, S.E., Lee, K.H., Kim, Y.S., Lee, S.H., Baik, E.J., Moon, C.H., Jung, Y.S.(2009) Effects of KR-33028, a novel Na+/H+ exchanger-1 inhibitor, on glutamate-induced neuronal cell death and ischemia-induced cerebral infarct. Brain Res. 2009 Jan 12;1248:22-30.

56. Gee, H.Y., Park, H.W., Kim, K.W. and Lee, M.G. PDZ-based adaptor proteins in epithelial anion transport and VIP receptor regulation The Journal of Medical Investigation 2009 Dec. 56 : 302-305 Mini Review.

57. Park, H.W., Nam, J.H., Kim, J.Y., Namkung, W., Yoon, J.S., Lee, J.S., Kim, K.S., Viktoria Venglovecz, Michael A. Gray, Kim, K.H. and Lee, M.G. Dynamic Regulation of CFTR Bicarbonate Permeability by [Cl-]i and its Role in Pancreatic Bicarbonate Secretion Gastroenterology 2010 Apr

58. Lee, J.S., Lee, Y.M., Kim, J.Y., Park, H.W., Sergio Grinstein, John Orlowski,
Kim, E.J., Kim, K.H. and Lee, M.G. ©¬Pix Up-regulates Na+/H+ Exchanger 3 through a
Shank2-mediated Protein-Protein Interaction JOURNAL OF BIOLOGICAL CHEMISTRY 2010 Mar 285(11) : 8104-8113

59. Kim, W.J., Lee, J.H., Yi, J.H., Cho, Y.J., Heo, J., Lee, S.H., Kim, S.W., Kim, M.K., Kim, K.H., Lee, B.I. and Lee, M.G A nonsynonymous variation in MRP2/ABCC2 is associated with neurological adverse drug reactions of carbamazepine in patients with epilepsy Pharmacogenetics and Genomics 2010 20(4):1744-6872

60. Lee, S.H., Lee, M.S., Lee, J.H., Kim, S.W., Kang, R.H., Choi, M.H., Park, S.H., Kim, S.J., Lee, J.M., Susan P.C. Cole, and Lee, M.G. MRP1 Polymorphisms Associated With Citalopram
Response in Patients With Major Depression Journal of Clinical Psychopharmacology 2010 Apr 30(2):116-125

61. Kwak, J.O., Lee, S.H., Lee, G.S., Kim, M.S., Ahn, Y.G., Lee, J.H., Kim, S.W., Kim, K.H. and Lee, M.G. Selective inhibition of MDR1 (ABCB1) by HM30181 increases oral bioavailability and therapeutic efficacy of paclitaxel European Journal of Pharmacology 2010 Feb 627:92-98



1. Kim, G.S., Lee, M.G., & Kim, K.H. (1991) Influence of thyroid hormone on exocrine function
of ratpancreas. Kor. J. Gastroenterol. 23:737-749

2. Kim, K.H., Lee, M.G., & Bang, Y.O. (1992) Mechanism of camostat-induced changes of
pancreatic exocrine function in rats. Kor. J. Gastroenterol. 24:593-604

3. Lee, M.G., & Kim, K.H. (1992) Analysis of human pancreatic juice proteins by high-performance
liquid chromatogrphy using hydrophobic interaction column. Kor. J. Gastroenterol.
24:1423-1433

4. Kim, N.K., Lee, K.S., Lee, M.G., & Kim, K.H. (1994) The early changes of exocrine pancreas
and the induction of acute pancreatitis after irradiation in rats. Kor. J. Gastroenterol.
26:716-727

5. Kim, K.H., Kim, D.G., Lee, M.G., Kim, C., & Lee, J.E. (1995) Effects of camostat and
cholecystokinin on oleic acid-induced pancreatic insufficiency in rats. Kor. J.
Gastroenterol. 27:96-109

6. Kim, J.S., Park, K.Y., Lee, M.G., Kim, Y.S., Ahn, J.B., & Yoon, H.J. (1995) Rapid and
type-specific detection of human influenzaviruses using reverse transcription-polymerase
chain reaction. J. Korean Soc. Microbiol. 30:233-243

7. Lee, M.G., Ahn, W., Choi, J.Y., Muallem, S., Kim, K.H. (2000) A novel Na+dependent
transporter and NHE3 mediate H efflux in the luminal membrane of the pancreatic duct:
regulation by cAMP. J. Korean Med. Sci. 15:S29-S30

8. Shin, D.M., Lee, M.G., Luo, X., Muallem, S. (2000) Receptor-specific Ca2 signaling in
polarized cells. J. Korean Med. Sci. 15 :S46-S48

9. Jung, Y., Ha, H., Jung, S.H., Lee, M.G., Lee, H.W., Yoon, J., Choi, J.W., Yeh, B.L.
(2001) F508 amino acid deletion mutation of CFTR gene in Korean lung cancer patients.
Exp Mol Med. 33:29-31

10. Lee, M.G. (2001) ABC transporter. Biochemistry News 21:125-129

11. Lee, M.G., Kim, J. W., Kim, K. H., Muallem, S. (2002) Molecular mechanism of pancreatic
bicarbonate secretion. Korean J Physiol Pharmacol. 6:131-138

12. Choi, J.H., Lee, M.G. (2003) ABC transporters and drug transport. J Kor Clin Pharmacol Ther. 11, 80-90

13. Gee, H.Y., Kim, C.K., Kim, S.W., Lee, J.H., Kim, J. H., Kim, K.H. and Lee, M.G. The L441P Mutation of Cystic Fibrosis Transmembrane conductance Regulator and its Molecular Pathogenic Mechanisms in a Korean Patient with Cystic Fibrosis: J Korean Med Sci 2010; 25: 166-71

14. Lee, S.H., Lee, M.G. (2008) Drug metabolism and drug-induced liver damage: A pharmacogenomic view point. Kor. J. Gastroenterol. 51 (4) Suppl. 109-116

15. Ahn, K.M., Park, H.Y., Lee, J.H., Lee, M.G., Kim, J.H., Kang, I.J., Lee, S.I. (2005) Cystic fibrosis in Korean children : a case report identified by a quantitative pilocarpine iontophoresis sweat test and genetic analysis. J Korean Med Sci. , 20:153-7

 
 
 
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